Antibiotic May Double Kidney Disease Risk

kidney disoders

The study says people taking the drugs have double the risk of developing kidney problems while they are on the medication than people who aren’t taking these drugs.

The authors say that in actual numbers that means an additional case of kidney injury for every 1,529 people taking oral fluoroquinolones. Drugs in this class include ciprofloxacin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin and norfloxacin.

The study says this effect is not seen with other commonly used antibiotics like amoxicillin and azithromycin.The research is published in this week’s issue of the Canadian Medical Association Journal.The researchers are from the U.S. Food and Drug Administration, the University of Florida in Gainesville, Fla., the therapeutic evaluative unit of the University of British Columbia in Vancouver, McGill University Health Centre in Montreal and the University of Washington in Seattle,

A class of commonly used medications may double your risk for kidney disease, according to research published today in the Canadian Medical Association Journal.

Using a health insurance database, researchers looked at men between the ages of 40 and 85 who took a class of antibiotics known as fluoroquinolones, which include ciprofloxacin, levofloxacin and moxifloxacin. They found that when compared to men who had not taken the antibiotics, men who took it were twice as likely to develop acute kidney disease, which can lead to a need for dialysis or kidney transplant.


“We found a twofold increased risk of acute kidney injury requiring hospital admission with the use of fluoroquinolone antibiotics,” the researchers, led by Mahyar Etmina MD, a researcher with the Child & Family Research Institute at the University of British Columbia, wrote in the study. “We did not find increased risk of acute kidney injury with other antibiotics.”

Men who were also taking certain types of cardiovascular medications, such as ACE inhibitors, were at an even higher risk, but the increased was only seen during the time the medication was used, according to the study; past use did not increase risk.

Antibiotics are medicines used in the treatment and prevention of bacterial infections, either by killing the bacteria or stop them from multiplying. They are either derived from microorganisms or synthetically produced and are not effective in treating viral infections such as influenza or the common cold.

There are many different types of antibiotics, targeting at different bacteria. The choice of antibiotics depends on factors such as the infection-causing bacteria, patient’s history of drug allergy and the site of infection. Therefore, it is of utmost importance that medical advice is sought before using any antibiotics.