DAU-SADAF (PSORIASIS)


PSORIASIS

Da-al-sadaf (psoriasis) has not  been mentioned in any classic medical literature. However, it was mentioned in Unani medicine and in as Kust Kutam.  In recent times, psoriasis has been identified as an independent disease or skin disorder and described in its present form.   Da-al-sadaf is derived from two Arabic words  Daun (= disease) and Al-Sadaf’ (= oyster shell), while psoriasis is derived from a Greek words so-ri-a-sis, which means itching. 

CAUSES OF  DAU-SADAF (PSORIASIS) 

According to Unani concept, the main causes of da-al- Sadaf is abnormal humours (Sauda e Mohtaraq, Merah-e-Sauda and Balgham-e-Shor)

OTHER CAUSES ARE DAU-SADAF IS

cold & dry and salty diet,

red meat, 

low calcium and high iodine diet, 

mental stress, 

trauma, 

infections, 

sunlight, 

puberty, 

pregnancy, 

drugs (antimalarial, β–blockers,

antimalignant, 

immuno-suppressive and NSAID)

Low humidity and cold weather 

PATHOGENESIS OF DAU-SADAF) PSORIASIS) 

The great Unani scholars described that when the khilt-e-sauda moves towards the skin,  then the tabiyat (homeostasis) of the body differs from the skin, Therefore the skin neither gets nourishment from that khilt (humour) nor excretes it, which makes the skin scaly. 

USOOLE ILAJ (MANAGEMENT) OF DA – UL- SADAF (PSORIASIS) 

1.Nuzuj wa Tanqiyah-e-Akhlat-e-Ghair Tabayiah 

(concoction and expulsion of abnormal humour) specially, Sauda   (melancholic humor)

2.Tahleel-e-auram(resolution of inflammation)

3.Tasfeeh-e-dam (blood purification)

4.Indemal-e-zakhm  (Cicatrization)

5.Taskeen-e-Jild  (demulcefication)

6.Tarteeb-e-umoomi wa muqami (general and local moisturization) 

ILAJ  BIL ADVIYA OF DAU-SADAF( PSORIASIS) 

ACCORDING TO USOOLE ILAJ THE TREATMENT WILL FOLLOW 

FOR NUZUJ WA  TANQIYAH-E-AKHLAT-E-GHAIR TABAYIAH   (concoction and expulsion of abnormal humour) specially, Sauda   (melancholic humor)

GIVE 

1.Aftimoon wilaiti  (Cuscuta reflexa Roxb. ), 

2.Tukhm-e-Babchi (Psoralia corylifolia Linn), 

3.Bisfaij Fistaqi (Polypodium vulgaris Linn),

4.Ghariqoon  (Polyporus officinalis Fries) 

5.Turanjbeen(Fraxinus ornus)

FOR TAHLEEL-E-AURAM (RESOLUTION OF INFLAMMATION )

GIVE 

1.Mako (Solanum nigrum Linn )

2.Kasni (Cichorium intybus Linn.), 

3.Brinjasif  (Artimisia vulgaris Linn.)

FOR TASFEEH-E-DAM  (BLOOD PURIFICATION )

GIVE 

1.Shahatra (Fumaric parviflora Lam.)

2.Unnab (Zizyphusvulgaris Lam.)

3.Chiraita (Swertia chirata)  

4.Sarphoka (Tephrosia purpurea (Linn.) 

5.Ushba maghrabi (Smilax aspera  , Karela (Momordica charantia Linn.); 

FOR INDEMAL-E-ZAKHM  (CICATRIZATION )

GIVE 

1.Sendoor (plumbum)

2.Sang-e-Jarahat (Silicate of magnesia),

3.Mazu (Quercus infectoria Oliv.)

4.Hina (Lawsonia inermisLinn)

FOR TASKEEN-E-JILD  (DEMULCEFICATION )

GIVE 

Behdana(Cydonia vulgaris Pers.)

Unnab (Zizyphus vulgaris Lamk.),

Tukhm-e-kahu (Lactuca scariola Linn), 

Samagh-e-arabi(Acacia arabica Willd); 

FOR TARTEEB-E-UMOOMI WA MUQAMI (GENERAL AND LOCAL MOISTURIZATION ) 

GIVE 

1.Arq-e-gulab (rose water)

2.Roghan-e-badam (almond oil),

3.Roghan Zaitoon (oliv oil), 

Roghan-e-narjeel (coconut oil) 

FOR JALI  (DETERGENTS)

GIVE 

1.Neem (Azadiracta indicaLinn.), 

2.haldi (curcuma longa Linn.)

3.Kamela (Mallotus philippinensis Muel.

VERY EFFECTIVE EXTRERNAL APPLICATION NUSKHA FOR PSORIASIS 

MARHAM-E-BUSOOR WA  QUROOH is beneficial in psoriatic patients in clinical practice 

THE NUSKHA OF MARHAME -E-BUSOOR WA  QUROOH    per 20 gm

Name of ingredients

Quantity in gms

Sendoor (Plumbum) 0.09

Mom (Bee’s wax) 1.82

Boric Acid (Boracic acid)9.00

Carbolic Acid (Phenol) 0.09

Roghan-e-Narjeel (Coconut Oil) 9.00 

make the Marham and apply

Tukhm-e-Babchi (Psoralia corylifolia Linn. seeds) are odourless but on chewing they emit a pungent odour and have a bitter unpleasant acrid taste derived from babchi(Psoralia corylifolia Linn.) plant.  They are hot and dry in nature. Psoralen and Isopsoralen are considered therapeutically active constituents of these seeds. They are specially recommended in the treatment of leucoderma, leprosy, psoriasis and other inflammatory diseases of the skin.

The antibacterial activity of the seeds of Psoralea corylifolia has already been documented.  The extract of seeds has shown antibacterial activity against some of the oral bacterial species tested.

Hence the study was done to evaluate the antibacterial effect of seeds of Psoralea corylifolia against some of the bacterial pathogens.  The aqueous, chloroform and ethanolic extract of seeds of Psoralea corylifolia were tested for their activity against 10 different species.

The extract showed no activity against Shigella dysenteriae, Bacillus cereus, Salmonella typhi, Actinomyces viscosus and Vibrio cholerae where as Escherichia coli, Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa and Enterococcus faecium were inhibited.

 The aqueous extract of seeds showed more inhibition than the chloroform and ethanolic extracts against all the species of bacteria that were inhibited.  Antibacterial effect of aqueous & chloroform extract of seeds were higher than the ethanolic extract against Staphylococcus aureus.

The chloroform extract showed more inhibition against Pseudomonas aeruginosa, when compared to the inhibitory action of the ethanolic and aqueous extract of seeds.   The ethanolic extract of seed was more active against Enterococcus faecium.  The antimicrobial effect of Psoralea corylifolia seeds may be due to the presence of secondary metabolites, one of the compound, Bakuchiol which is a alkaloid was found to possess antibacterial effect on oral bacterias.   Further analysis of the compounds and their testing against micro-organisms would  help to develop a new antimicrobial agent that may be of great importance.

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